Siren's Kiss is a gripping mystery drama that delves into the dark life of Han Seol-ah, an art auctioneer shadowed by the sudden deaths of every man who has loved her. When insurance investigator Cha Woo-seok discovers a suspicious pattern connecting these tragic fatalities to insurance fraud, he decides to get closer to the truth by going undercover as her lover. As he uncovers evidence of stolen art and buried secrets, the line between victim and perpetrator becomes increasingly blurred. 

The show challenges viewers to decide whether Seol-ah is a dangerous femme fatale or a trapped soul caught in a lethal cycle she never built.