Steel Ball Run is set in the late 19th century United States and tells the story of Johnny Joestar, a former jockey whose career was cut short after a tragic accident left him unable to walk. Struggling with bitterness and searching for purpose, Johnny crosses paths with Gyro Zeppeli, a mysterious outlaw armed with unique steel ball techniques. Drawn to Gyro’s charisma and determination, Johnny forms an unlikely alliance with him and enters the Steel Ball Run, a grueling cross-continental horse race stretching from San Diego to New York.